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Seth J. Welsh
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Journal Articles

ETV4-Dependent Transcriptional Plasticity Maintains MYC Expression and Results in IMiD Resistance in Multiple Myeloma

Open Access
Paola Neri, Benjamin G. Barwick, David Jung, Jonathan C. Patton, Ranjan Maity, Ines Tagoug, Caleb K. Stein, Remi Tilmont, Noemie Leblay, Sungwoo Ahn, Holly Lee, Seth J. Welsh, Daniel L. Riggs, Nicholas Stong, Erin Flynt, Anjan Thakurta, Jonathan J. Keats, Sagar Lonial, P. Leif Bergsagel, Lawrence H. Boise, Nizar J. Bahlis
Journal: Blood Cancer Discovery
Blood Cancer Discov (2024) 5 (1): 56–73.
https://doi.org/10.1158/2643-3230.BCD-23-0061
Published: 08 January 2024
View article titled, ETV4-Dependent Transcriptional Plasticity Maintains MYC Expression and Results in IMiD Resistance in Multiple Myeloma
Open the PDF for ETV4-Dependent Transcriptional Plasticity Maintains MYC Expression and Results in IMiD Resistance in Multiple Myeloma in another window
Includes: Supplementary data
Journal Articles

Transcriptional Heterogeneity Overcomes Super-Enhancer Disrupting Drug Combinations in Multiple Myeloma

Open Access
Seth J. Welsh, Benjamin G. Barwick, Erin W. Meermeier, Daniel L. Riggs, Chang-Xin Shi, Yuan Xiao Zhu, Meaghen E. Sharik, Megan T. Du, Leslie D. Abrego Rocha, Victoria M. Garbitt, Caleb K. Stein, Joachim L. Petit, Nathalie Meurice, Yuliza Tafoya Alvarado, Rodrigo Fonseca, Kennedi T. Todd, Sochilt Brown, Zachery J. Hammond, Nicklus H. Cuc, Courtney Wittenberg, Camille Herzog, Anna V. Roschke, Yulia N. Demchenko, Wei-dong D. Chen, Peng Li, Wei Liao, Warren J. Leonard, Sagar Lonial, Nizar J. Bahlis, Paola Neri, Lawrence H. Boise, Marta Chesi, P. Leif Bergsagel
Journal: Blood Cancer Discovery
Blood Cancer Discov (2024) 5 (1): 34–55.
https://doi.org/10.1158/2643-3230.BCD-23-0062
Published: 08 January 2024
View article titled, Transcriptional Heterogeneity Overcomes Super-Enhancer Disrupting Drug Combinations in Multiple Myeloma
Open the PDF for Transcriptional Heterogeneity Overcomes Super-Enhancer Disrupting Drug Combinations in Multiple Myeloma in another window
Includes: Supplementary data
Journal Articles

Tumor Burden Limits Bispecific Antibody Efficacy through T-cell Exhaustion Averted by Concurrent Cytotoxic Therapy

Free
Erin W. Meermeier, Seth J. Welsh, Meaghen E. Sharik, Megan T. Du, Victoria M. Garbitt, Daniel L. Riggs, Chang-Xin Shi, Caleb K. Stein, Marco Bergsagel, Bryant Chau, Matthew L. Wheeler, Natalie Bezman, Feng Wang, Pavel Strop, P. Leif Bergsagel, Marta Chesi
Journal: Blood Cancer Discovery
Blood Cancer Discov (2021) 2 (4): 354–369.
https://doi.org/10.1158/2643-3230.BCD-21-0038
Published: 01 July 2021
View article titled, Tumor Burden Limits Bispecific Antibody Efficacy through T-cell Exhaustion Averted by Concurrent Cytotoxic Therapy
Open the PDF for Tumor Burden Limits Bispecific Antibody Efficacy through T-cell Exhaustion Averted by Concurrent Cytotoxic Therapy in another window
Includes: Supplementary data
Journal Articles

Monosomic Loss of MIR15A/MIR16-1 Is a Driver of Multiple Myeloma Proliferation and Disease Progression

Available to Purchase
Marta Chesi, Caleb K. Stein, Victoria M. Garbitt, Meaghen E. Sharik, Yan W. Asmann, Matteo Bergsagel, Daniel L. Riggs, Seth J. Welsh, Erin W. Meermeier, Shaji K. Kumar, Esteban Braggio, P. Leif Bergsagel
Journal: Blood Cancer Discovery
Blood Cancer Discov (2020) 1 (1): 68–81.
https://doi.org/10.1158/0008-5472.BCD-19-0068
Published: 19 June 2020
View article titled, Monosomic Loss of MIR15A/MIR16-1 Is a Driver of Multiple Myeloma Proliferation and Disease Progression
Open the PDF for Monosomic Loss of MIR15A/MIR16-1 Is a Driver of Multiple Myeloma Proliferation and Disease Progression in another window
Includes: Supplementary data