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Guillermo Garcia-Manero
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Journal Articles

A Phase Ib/II Study of Ivosidenib with Venetoclax ± Azacitidine in IDH1-Mutated Myeloid Malignancies

Curtis A. Lachowiez, Sanam Loghavi, Zhihong Zeng, Tomoyuki Tanaka, Yi June Kim, Hidetaka Uryu, Sven Turkalj, Niels Asger Jakobsen, Marlise R. Luskin, Dzifa Y. Duose, Rebecca S.S. Tidwell, Nicholas J. Short, Gautam Borthakur, Tapan M. Kadia, Lucia Masarova, George D. Tippett, Prithviraj Bose, Elias J. Jabbour, Farhad Ravandi, Naval G. Daver, Guillermo Garcia-Manero, Hagop Kantarjian, Jacqueline S. Garcia, Paresh Vyas, Koichi Takahashi, Marina Konopleva, Courtney D. DiNardo
Journal: Blood Cancer Discovery
Blood Cancer Discov (2023) 4 (4): 276–293.
https://doi.org/10.1158/2643-3230.BCD-22-0205
Published: 05 July 2023
View article titled, A Phase Ib/II Study of Ivosidenib with Venetoclax ± Azacitidine in <em>IDH1</em>-Mutated Myeloid Malignancies
Open the PDF for A Phase Ib/II Study of Ivosidenib with Venetoclax ± Azacitidine in <em>IDH1</em>-Mutated Myeloid Malignancies in another window
Includes: Supplementary data
Journal Articles

Abstract A50: Distinguishing Mosaic Li Fraumeni Syndrome, Clonal Hematopoiesis and Incidental Myeloid Neoplasms in Patients with Solid Tumors with Pathogenic TP53 Mutations Identified by Germline Testing or Cell-Free Circulating DNA Sequencing

Sanam Loghavi, Yoheved Gerstein, Mark J Routbort, Keyur P Patel, Koichi Takahashi, Molly Daniels, Julie Moskowitz, Danielle E Hammond, Kelly Chien, L. Jeffrey Medeiros, Farhad Ravandi, Hagop M Kantarjian, Guillermo Garcia-Manero, Banu Arun, Joseph D Khoury, Courtney D DiNardo
Journal: Blood Cancer Discovery
Blood Cancer Discov (2023) 4 (3_Supplement): A50.
https://doi.org/10.1158/2643-3249.AML23-A50
Published: 01 May 2023
View article titled, Abstract A50: Distinguishing Mosaic Li Fraumeni Syndrome, Clonal Hematopoiesis and Incidental Myeloid Neoplasms in Patients with Solid Tumors with Pathogenic TP53 Mutations Identified by Germline Testing or Cell-Free Circulating DNA Sequencing
Journal Articles

Targeting the EIF2AK1 Signaling Pathway Rescues Red Blood Cell Production in SF3B1-Mutant Myelodysplastic Syndromes With Ringed Sideroblasts

Vera Adema, Feiyang Ma, Rashmi Kanagal-Shamanna, Natthakan Thongon, Guillermo Montalban-Bravo, Hui Yang, Scott A. Peslak, Feng Wang, Pamela Acha, Francesc Sole, Pamela Lockyer, Margherita Cassari, Jaroslaw P. Maciejewski, Valeria Visconte, Irene Gañán-Gómez, Yuanbin Song, Carlos Bueso-Ramos, Matteo Pellegrini, Tuyet M. Tan, Rafael Bejar, Jennifer S. Carew, Stephanie Halene, Valeria Santini, Gheath Al-Atrash, Karen Clise-Dwyer, Guillermo Garcia-Manero, Gerd A. Blobel, Simona Colla
Journal: Blood Cancer Discovery
Blood Cancer Discov (2022) 3 (6): 554–567.
https://doi.org/10.1158/2643-3230.BCD-21-0220
Published: 02 November 2022
View article titled, Targeting the EIF2AK1 Signaling Pathway Rescues Red Blood Cell Production in <em>SF3B1</em>-Mutant Myelodysplastic Syndromes With Ringed Sideroblasts
Open the PDF for Targeting the EIF2AK1 Signaling Pathway Rescues Red Blood Cell Production in <em>SF3B1</em>-Mutant Myelodysplastic Syndromes With Ringed Sideroblasts in another window
Includes: Supplementary data
Journal Articles

Clonal Hematopoiesis Is Associated with Increased Risk of Severe Neurotoxicity in Axicabtagene Ciloleucel Therapy of Large B-Cell Lymphoma

Neeraj Y. Saini, David M. Swoboda, Uri Greenbaum, Junsheng Ma, Romil D. Patel, Kartik Devashish, Kaberi Das, Mark R. Tanner, Paolo Strati, Ranjit Nair, Luis Fayad, Sairah Ahmed, Hun Ju Lee, Swaminathan P. Iyer, Raphael Steiner, Nitin Jain, Loretta Nastoupil, Sanam Loghavi, Guilin Tang, Roland L. Bassett, Preetesh Jain, Michael Wang, Jason R. Westin, Michael R. Green, David A. Sallman, Eric Padron, Marco L. Davila, Frederick L. Locke, Richard E. Champlin, Guillermo Garcia-Manero, Elizabeth J. Shpall, Partow Kebriaei, Christopher R. Flowers, Michael D. Jain, Feng Wang, Andrew P. Futreal, Nancy Gillis, Sattva S. Neelapu, Koichi Takahashi
Journal: Blood Cancer Discovery
Blood Cancer Discov (2022) 3 (5): 385–393.
https://doi.org/10.1158/2643-3230.BCD-21-0177
Published: 06 September 2022
View article titled, Clonal Hematopoiesis Is Associated with Increased Risk of Severe Neurotoxicity in Axicabtagene Ciloleucel Therapy of Large B-Cell Lymphoma
Open the PDF for Clonal Hematopoiesis Is Associated with Increased Risk of Severe Neurotoxicity in Axicabtagene Ciloleucel Therapy of Large B-Cell Lymphoma in another window
Includes: Supplementary data
Journal Articles

Patterns of Resistance Differ in Patients with Acute Myeloid Leukemia Treated with Type I versus Type II FLT3 Inhibitors

Ahmad S. Alotaibi, Musa Yilmaz, Rashmi Kanagal-Shamanna, Sanam Loghavi, Tapan M. Kadia, Courtney D. DiNardo, Gautam Borthakur, Marina Konopleva, Sherry A. Pierce, Sa A. Wang, Guilin Tang, Veronica Guerra, Bachar Samra, Naveen Pemmaraju, Elias Jabbour, Nicholas J. Short, Ghayas C. Issa, Maro Ohanian, Guillermo Garcia-Manero, Kapil N. Bhalla, Keyur P. Patel, Koichi Takahashi, Michael Andreeff, Jorge E. Cortes, Hagop M. Kantarjian, Farhad Ravandi, Naval Daver
Journal: Blood Cancer Discovery
Blood Cancer Discov (2021) 2 (2): 125–134.
https://doi.org/10.1158/2643-3230.BCD-20-0143
Published: 01 March 2021
View article titled, Patterns of Resistance Differ in Patients with Acute Myeloid Leukemia Treated with Type I versus Type II FLT3 Inhibitors
Open the PDF for Patterns of Resistance Differ in Patients with Acute Myeloid Leukemia Treated with Type I versus Type II FLT3 Inhibitors in another window