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Research Articles

Multiple myeloma patients treated with anti-BCMA bispecific antibodies develop profound hypogammaglobulinemia and susceptibility to infections. Immunoglobulin replacement mitigates the risk of serious infections.

Ex vivo screening of primary AML samples for susceptibility to venetoclax-based drug combinations identify potentially effective combinations and patient characteristics associated with response.

A mass spectrometry–based immunopeptidomics characterizes the antigenic landscape of primary leukemic stem and progenitor cells in acute myeloid leukemia, identifying prime targets for the development of T cell–based immunotherapies targeting leukemia-repopulating cells.

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