Immunosuppressive Extracellular Vesicles in CLL Available to Purchase

Cancer cells need to evade the immune system for their progression. In this issue of Blood Cancer Discovery, Gargiulo and colleagues report that in a mouse model of chronic lymphocytic leukemia, small extracellular vesicles inhibit antitumor immunity by altering CD8 T-cell transcriptome, proteome, and metabolome.

See related article by Gargiulo et al., p. 54 (9).