Skip to Main Content

Advertisement

Skip Nav Destination
photo of Elaine R. Mardis, PhD photo of Lillian L. Siu, MD

Editors-In-Chief


Elaine R. Mardis, PhD
Nationwide Children's Hospital
The Ohio State University

Lillian L. Siu, MD
Princess Margaret Cancer Centre
University of Toronto

Editors-In-Chief

Elaine R. Mardis, PhD
Nationwide Children's Hospital
The Ohio State University
    
Lillian L. Siu, MD
Princess Margaret Cancer Centre
University of Toronto

Editors' Corner

Reflecting on Year One of Cancer Research Communications

Cancer Research Communications officially launched in October of 2021, but its conception and development began many months before. The journal was officially announced at the AACR Annual Meeting 2021...(read more)

 

Journal Sections

Cancer Research Communications welcomes high-quality research spanning the full spectrum of cancer science and medicine. This open access journal expands the AACR journal portfolio, stimulates the exchange of new ideas and approaches, and provides a rapid publication pathway. The below sections reflect the breadth of this new journal’s scope.

Featured Articles

Molecular and Cellular Biology
Kristie A. Blum, Jeffrey G. Supko et al.
NF-κB, a transcription factor essential for inflammatory responses, is constitutively activated in many lymphomas. In preclinical studies, pelabresib (CPI-0610), an investigational (BET) bromodomain inhibitor, downregulated NF-κB signaling and demonstrated antitumor activity in vitro. Here we report the safety, ...
Immuno-oncology
Caroline Phillips, Inder Bhamra et al.
Wnt signalling is implicated in the etiology of gastrointestinal tract cancers. Targeting Wnt signalling is challenging due to on-target toxicity concerns and lack of druggable pathway components. We describe the discovery and characterization of RXC004, a potent and selective inhibitor of the ...
Emerging Technologies and Data Science
Natalia E. Cortez, Cecilia Rodriguez Lanzi et al.
Pancreatic ductal adenocarcinoma (PDAC) continues to be a major health problem. A ketogenic diet (KD), characterized by a very low carbohydrate and high fat composition, has gained attention for its anti-tumor potential. We evaluated the effect and mechanisms of feeding a strict KD alone or in combination with gemcitabine ...
Therapeutic Research and Development
Kyle A. Cottrell, Luisangely Soto-Torres et al.
The RNA editing enzyme ADAR is an attractive therapeutic target for multiple cancers. Through its deaminase activity, ADAR edits adenosine to inosine in double-stranded RNAs. Loss of ADAR in some cancer cell lines causes activation of the type I IFN pathway and the PKR translational repressor, leading to inhibition of ...
Precision Medicine and Biomarkers
Glenn J. Hanna, Alessandro Villa et al.
Oral leukoplakia is common and may, in some cases, progress to carcinoma. Proliferative leukoplakia is a progressive, often multifocal subtype with a high rate of malignant transformation compared with the more common localized leukoplakia. We hypothesized that the immune microenvironment and gene expression patterns ...
Close Modal

or Create an Account

Close Modal
Close Modal