Brain Cancer Collection
The AACR editors are proud to present this selection of impactful journal articles focusing on brain cancer, published from across the AACR journal portfolio.
Identification of RNA-binding protein LARP4B as a tumor suppressor in glioma.
Koso H, Yi H, Sheridan P, Miyano S, Ino Y, Todo T, et al. Cancer Research 2016; DOI:10.1158/00085472.CAN152308. [Published OnlineFirst March 1, 2016].
Drosophila brat and human ortholog TRIM3 maintain stem cell equilibrium and suppress brain tumorigenesis by attenuating Notch nuclear transport.
Mukherjee S, Tucker-Burden C, Zhang C, Moberg K, Read R, Hadjipanayis C, et al. Cancer Research 2016; DOI: 10.1158/00085472.CAN152299. [Published OnlineFirst February 18, 2016].
ABCG2 and ABCB1 limit the efficacy of dasatinib in a PDGF-Bdriven brainstem glioma model.
Mittapalli RK, Chung AH, Parrish KE, Crabtree D, Halvorson KG, Hu G, et al. Molecular Cancer Therapeutics 2016; DOI:10.1158/15357163.MCT150093. [Published OnlineFirst February 16, 2016].
Vaccination with irradiated autologous tumor cells mixed with irradiated GM-K562 cells stimulates anti-tumor immunity and T-lymphocyte activation in patients with recurrent malignant glioma.
Curry WT, Gorrepati R, Piesche M, Sasada T, Agarwalla PK, Jones PS, et al. Clinical Cancer Research 2016; DOI:10.1158/10780432.CCR152163. [Published OnlineFirst February 12, 2016].
Mastermind-like 3 controls proliferation and differentiation in neuroblastoma. strong>
Heynen GJJE, Nevedomskaya E, Palit S, Basheer NJ, Lieftink C, Schlicker A. et al. Molecular Cancer Research 2016; DOI:10.1158/15417786.MCR150291T. [Published OnlineFirst January 19, 2016].
Approaching a scientific consensus on the association between allergies and glioma risk: a report from the Glioma International Case-Control Study.
Amirian ES, Zhou R, Wrensch MR, Olson SH, Scheurer ME, Il'yasova D, et al. Cancer Epidemiology, Biomarkers & Prevention 2016;25:28290.
Birth size characteristics and risk of brain tumors in early adulthood: results from a Swedish cohort study.
Tettamanti G, Ljung R, Mathiesen T, Schwartzbaum J, Feychting M. Cancer Epidemiology, Biomarkers & Prevention 2016;25:18.
Tigecycline inhibits glioma growth by regulating miRNA-199b-5pHES1AKT pathway.
Yang R, Yi L, Dong Z, Ouyang Q, Zhou J, Pang Y, et al. Molecular Cancer Therapeutics 2016;15:4219.
CAR T cells targeting podoplanin reduce orthotopic glioblastomas in mouse brains.
Shiina S, Ohno M, Ohka F, Kuramitsu S, Yamamichi A, Kato A, et al. Cancer Immunology Research 2016;4:12435.
SGEF is regulated via TWEAK/Fn14/NF-κB signaling and promotes survival by modulation of the DNA repair response to temozolomide.
Fortin Ensign SP, Roos A, Mathews IT, Dhruv HD, Tuncali S, Sarkaria JN, et al. Molecular Cancer Research 2016;14:30212.
Melanoma brain metastasis pseudoprogression after pembrolizumab treatment.
Cohen JV, Alomari AK, Vortmeyer AO, Jilaveanu LB, Goldberg SB, Mahajan A, et al. Cancer Immunology Research 2015;4:17982.
Glioblastoma eradication following immune checkpoint blockade in an orthotopic, immunocompetent model.
Reardon DA, Gokhale PC, Klein SR, Ligon KL, Rodig SJ, Ramkissoon SH, et al. Cancer Immunology Research 2016;4:12435.
Treatment response assessment in IDH-mutant glioma patients by noninvasive 3D functional spectroscopic mapping of 2-hydroxyglutarate.
Andronesi OC, Loebel F, Bogner W, Marjańska M, Vander Heiden MG, Iafrate AJ, et al. Clinical Cancer Research 2015; DOI:10.1158/10780432.CCR150656. [Published OnlineFirst November 3, 2015].
Crizotinib synergizes with chemotherapy in preclinical models of neuroblastoma.
Krytska K, Ryles HT, Sano R, Raman P, Infarinato NR, Hansel TD, et al. Clinical Cancer Research 2016;22:94860.
Genomic characterization of brain metastases reveals branched evolution and potential therapeutic targets.
Brastianos PK, Carter SL, Santagata, Cahill DP, Taylor-Weiner A, Jones RT, et al. Cancer Discovery 2015;5:116477.
Next-generation sequencing of stage IV squamous cell lung cancers reveals an association of PI3K aberrations and evidence of clonal heterogeneity in patients with brain metastases.
Paik PK, Shen R, Won H, Rekhtman N, Wang L, Sima CS, et al. Cancer Discovery 2015;5:61021.