The Best of the AACR Journals Collection: Author Profiles
Title & Affiliation:
Professor, Princeton University, Princeton, NJ
Q: What is your primary area of study/research?
Q: What influenced your decision to embark on a research career?
A: As a high school student, I obtained a summer internship at Duke Medical Center working in the lab of Dr. Bill Peters, who was pushing the frontiers of high-dose chemotherapy with autologous bone marrow transplant for breast cancer. He gave me the chance to do “real” research, including collecting samples from patients and testing them in the lab. I loved it and was hooked.
Q; What excites you most about your research area?
A: Metabolism is everywhere. We make metabolic choices every time we eat a meal. Cancer growth is absolutely dependent on metabolism, but for several decades, metabolism was viewed as nothing more than a housekeeping process. Now we know that it is highly regulated and highly controllable, both through diet and drugs. Because metabolism is subject to mass balance constraints that are not relevant in many areas of biology, it is also uniquely understandable. To me, understandable + actionable = exciting!
Q: What are your hobbies or passions outside of work?
A: Swimming at the beach, Tar Heel basketball, and my children.