The AACR editors are proud to present this selection of impactful journal articles focusing on genomics and big data, published from across the AACR journal portfolio.
- Systematic functional interrogation of rare cancer variants identifies oncogenic alleles.
Kim E…Hahn W. Cancer Discovery July 2016.
- Interaction landscape of inherited polymorphisms with somatic events in cancer.
Carter H…Ideker T. Cancer Discovery April 2017.
- The cancer epidemiology descriptive cohort database: a tool to support population-based interdisciplinary research.
Kennedy AE…Seminara D. Cancer Epidemiology, Biomarkers & Prevention October 2016.
- Whole-exome sequencing validates a preclinical mouse model for the prevention and treatment of cutaneous squamous cell carcinoma.
Knatko EV… Dinkova-Kostova AT. Cancer Prevention Research January 2017.
- High-throughput genomic profiling of adult solid tumors reveals novel insights into cancer pathogenesis.
Hartmaier RJ… Lipson D. Cancer Research February 2017.
- Cross-cancer genome-wide analysis of lung, ovary, breast, prostate, and colorectal cancer reveals novel pleiotropic associations.
Fehringer G… Hung RJ. Cancer Research September 2016.
- Multiplex genome editing to generate universal CAR T cells resistant to PD1 inhibition.
Ren J…Zhao Y. Clinical Cancer Research November 2016.
- Genome-Wide miRNA analysis identifies miR-188-3p as a novel prognostic marker and molecular factor involved in colorectal carcinogenesis.
Pichler M… Calin A. Clinical Cancer Research March 2017.
- Genomic amplification of CD274 (PD-L1) in small-cell lung cancer.
George J… Kohno T. Clinical Cancer Research March 2017.
- Genome-wide analyses identifies MEN1 and MAX mutations and a neuroendocrine-like molecular heterogeneity in quadruple WT GIST.
Pantaleo M… Biasco G. Molecular Cancer Research January 2017.
- Expression profiling of circulating microvesicles reveals intercellular transmission of oncogenic pathways.
Milani G… Kronnie G. Molecular Cancer Research January 2017.
- Genomic landscape of malignant mesotheliomas.
Kato S…Kurzrock R. Molecular Cancer Therapeutics October 2016.