In the Spotlight
New collection! Read the Molecular Cancer Research breast cancer collection. These articles are freely available, anytime anywhere. Find out more about the Journal.
Read Elsa Flores’s 75th Anniversary Commentary on “Apoptosis, p53, and Tumor Cell Sensitivity,” by Brown and Wouters. It was conventionally held that anticancer agents exerted their cytotoxic effects by inducing apoptosis in tumor cells, with mutations in p53 or apoptotic genes thus conferring drug resistance. Brown and Wouters put forth the experimental evidence against this viewpoint, leading to the adoption of a broader perspective regarding anticancer drug mechanisms of action and the factors underlying therapeutic resistance. Visit the 75th Anniversary page for more information.
In anticipation of the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, Molecular Cancer Therapeutics has put together two article collections related to the program: Antibody-Drug Conjugates and Experimental Models. View the Targets Collections and read the recently published articles.